<관심분야 및 연구분야>
Development of Cell Penetrating Peptides
Development of Biomaterials for targeted drug delivery
Mechanism of self-assembly of peptides
Transdermal drug delivery system

● Nam, S.H., Park, J. & Koo, H. Recent advances in selective and targeted drug/gene delivery systems using cell-penetrating peptides. Archives of Pharmacal Research, 1-17 (2023).

● Nam, S.H., Lee, Y., Yang, H.-J. & Park, S.B. The complex of miRNA2861 and cell-penetrating, dimeric a-helical peptide accelerates the osteogenesis of mesenchymal stem cells. (2022).

● Lim, S. et al. Effective cell penetration of negatively？charged proline？rich SAP (E) peptides with cysteine mutation. Peptide Science, e24301 (2022)

● Kang, S.-J., Nam, S.H. & Lee, B.-J. Engineering Approaches for the Development of Antimicrobial Peptide-Based Antibiotics. Antibiotics 11, 1338 (2022)

● Nam, S.H. et al. pH-Activatable cell penetrating peptide dimers for potent delivery of anticancer drug to triple-negative breast cancer. Journal of Controlled Release 330, 898-906 (2021).

● Hyun, S. et al. One-bead-one-compound screening approach to the identification of cyclic peptoid inhibitors of cyclophilin D as neuroprotective agents from mitochondrial dysfunction. Chemical Communications 57, 2388-2391 (2021).

● Chong, S.-E. et al. Intracellular delivery of immunoglobulin G at nanomolar concentrations with domain Z-fused multimeric α-helical cell penetrating peptides. Journal of Controlled Release 330, 161-172 (2021).

● Chong, S.-E. et al. A dimeric α-helical cell penetrating peptide mounted with an HER2-selective affibody. Biomaterials Science 9, 7826-7831 (2021).

● Nam, S.H. et al. Augmented osteogenesis of mesenchymal stem cells using a fragmented Runx2 mixed with cell-penetrating, dimeric a-helical peptide. European Journal of Pharmaceutical Sciences 144, 105210 (2020).

● Jung, D. et al. De novo formation of citrate-based fluorophores on N-termini of peptides and proteins in cells and tissues. Chemical Communications 56, 74-77 (2020).

● Ha, M. et al. Highly efficient photothermal therapy with cell-penetrating peptide-modified bumpy Au triangular nanoprisms using low laser power and low probe dose. Nano Letters 21, 731-739 (2020).

● Ahn, J.H. et al. Reversible Protein Conjugation on Live Cell Surfaces by Specific Recognition between Coiled-Coil Motifs of Natural Amino Acid Sequences. Biomacromolecules 21, 3539-3546 (2020).

● Kang, M. et al. Calcium-binding polymer-coated poly (lactide-co-glycolide) microparticles for sustained release of quorum sensing inhibitors to prevent biofilm formation on hydroxyapatite surfaces. ACS applied materials & interfaces 11, 7686-7694 (2019).

● Oh, J.H. et al. Multimeric Amphipathic α?Helical Sequences for Rapid and Efficient Intracellular Protein Transport at Nanomolar Concentrations. Advanced Science 5, 1800240 (2018).

● Kwon, S.R. et al. Drug Delivery: Electrodeless Reverse Electrodialysis Patches as an Ionic Power Source for Active Transdermal Drug Delivery (Adv. Funct. Mater. 15/2018). Advanced Functional Materials 28, 1870100 (2018).

● Kwon, S.R. et al. Electrodeless reverse electrodialysis patches as an ionic power source for active transdermal drug delivery. Advanced Functional Materials 28, 1705952 (2018).

● Kim, H. et al. Ring Opening Metathesis Polymerization of Bicyclic α, β?Unsaturated Anhydrides for Ready?to?be?grafted Polymers Having Tailored pH?Responsive Degradability. Angewandte Chemie 130, 12648-12652 (2018).
● Kim, G.C. et al. Photoswitching of cell penetration of amphipathic peptides by control of α-helical conformation. Biomacromolecules 19, 2863-2869 (2018).