[연구분야]
스트레스성 질환 및 뇌질환(치매, 불안, 우울증 등)의 작용기전 연구
노화억제 및 뇌질환 치료제제 개발 연구
임상연구
천연물의약품 성분분석 및 유효물질 추출
신약개발 AI 솔루션(약물 후보물질 라이브러리 탐색, 액물-타겟 효과 예측 등) 연구

[학술논문]
J. H. Yoon, S. H. Lim, I.-S. Lee, Y. K. Jang, S. J. Park, S. J. Lee, S. Im, J.-H. Park, H. Park, S. Maeng*, J. Shin*, 'Schisandra chinensis Pomace Attenuates Scopolamine-Induced Cholinergic Dysfunction Associated with Changes in BDNF and JNK Signaling'
Current Issues in Molecular Biology, 48, 390, 2026.

J. H. Yoon, D. J. Jung, M. Kim, Y.-N. Kim, M. Shim, S. Y. Lee, C. Shin, S. Im, S. Maeng*, J. Shin*,
'Gami-Guibitang Attenuates Anxiety-Like Behaviors and Modulates Hippocampal Synaptic Signaling in a Valproic Acid-Induced Mouse Model of Autism'
Brain Sciences, 16, 259, 2026.

M. Yang, G. Jung, J. Shin*,
'Cyclic ADP-Ribose Modulates Intracellular Calcium Homeostasis and Anagen-Associated Signaling Pathways in Human Hair Follicle Dermal Papilla Cells'
Applied Sciences, 16, 950, 2026.

J. H. Yoon, J. Maeng, Y. Kim, G. Koo, J. S. Shim, S. Im, S. Jung, J. Shin, S.-S. Kim*, S. Maeng*,
'Roasted Astragalus membranaceus Inhibits Cognitive Decline in 5xFAD Mice by Activating the BDNF/CREB Pathway'
Antioxidants, 14, 1250, 2025.

J. Kim, Y. Park, J. Shin, S. Kim, H. L. Kim, S. Bae*,
'Sustainable Protein Extraction from Spent Coffee Grounds Using Response Surface Methodology'
Biomass Conversion and Biorefinery, 2025.

J. Shin, J. Lee, J. Choi, B.-T. Ahn, S. C. Jang, S.-W. You, D.-Y. Koh, S. Maeng*, S.-Y. Cha*,
'Rapid-Onset Antidepressant-Like Effect of Nelumbinis semen in Social Hierarchy Stress Model of Depression'
Evidence-Based Complementary and Alternative Medicine, 2022, 6897359.

M. Kim, M. Song, H.-J. Oh, J. Hui, W. Bae, J. Shin, S.-D. Ji, Y. H. Koh, J. W. Suh, H. Park*, S. Maeng*,
'Evaluating the Memory Enhancing Effects of Angelica gigas in Mouse Models of Mild Cognitive Impairments'
Nutrients, 12, 97, 2020.

H. Park*, M. Kim*, J. Shin, J. Park, S. Y. Bang, C. Yi, M.-A. Kim, J.-H. Lew, J. W. Suh, S. Maeng*,
'Woohwangcheongsimwon Prevents High-Fat Diet-Induced Memory Deficits and Induces SIRT1 in Mice'
Journal of Medicinal Food, 21, 167-173, 2018.

J. Shin*, S. U. Son, H. Park, Y. Kim, S. H. Park, K. Swanberg, J.-Y. Shin, S.-K. Ha, Y. Cho, S.-Y. Bang, J.-H. Lew, S.-H. Cho, S. Maeng*,
'Preclinical Evidence of Rapid-Onset Antidepressant-Like Effect in Radix Polygalae Extract'
PLOS ONE, 9, e88617, 2014.

[특허]
항우울용, 스트레스 완화용 및 항 불안용 조성물_등록번호 10-2527193
인지기능 개선용, 기억력 개선용, 스트레스 완화용 및 항 불안용 조성물_등록번호 10-2527194
상표권 등록 [메디뉴런]_한국/40-1793085
상표권 등록 [브레인 알파]_한국/40-1793087